3sh0: Difference between revisions

Latest revision as of 15:56, 14 March 2024

Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1065Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1065

Structural highlights

3sh0 is a 2 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.84Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

UPPS_ECOLI Generates ditrans,octacis-undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) and farnesyl diphosphate (FPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.^[1]

References

↑ Chang SY, Ko TP, Liang PH, Wang AH. Catalytic mechanism revealed by the crystal structure of undecaprenyl pyrophosphate synthase in complex with sulfate, magnesium, and triton. J Biol Chem. 2003 Aug 1;278(31):29298-307. Epub 2003 May 19. PMID:12756244 doi:10.1074/jbc.M302687200

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OCA

[1] Chang SY, Ko TP, Liang PH, Wang AH. Catalytic mechanism revealed by the crystal structure of undecaprenyl pyrophosphate synthase in complex with sulfate, magnesium, and triton. J Biol Chem. 2003 Aug 1;278(31):29298-307. Epub 2003 May 19. PMID:12756244 doi:10.1074/jbc.M302687200

[1]

@@ Line 1: / Line 1: @@
-[[Image:3sh0.jpg|left|200px]]
-{{STRUCTURE_3sh0|  PDB=3sh0  |  SCENE=  }}
+==Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1065==
+<StructureSection load='3sh0' size='340' side='right'caption='[[3sh0]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3sh0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SH0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SH0 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.84&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAX:2-(DODECYLOXY)-6-HYDROXYBENZOIC+ACID'>SAX</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sh0 OCA], [https://pdbe.org/3sh0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sh0 RCSB], [https://www.ebi.ac.uk/pdbsum/3sh0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sh0 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/UPPS_ECOLI UPPS_ECOLI] Generates ditrans,octacis-undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) and farnesyl diphosphate (FPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.<ref>PMID:12756244</ref>
-===Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1065===
+==See Also==
+*[[Undecaprenyl pyrophosphate synthase 3D structures|Undecaprenyl pyrophosphate synthase 3D structures]]
+== References ==
-==About this Structure==
+<references/>
-[[3sh0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SH0 OCA].
+__TOC__
-[[Category: Di-trans,poly-cis-decaprenylcistransferase]]
+</StructureSection>
-[[Category: Escherichia coli k-12]]
+[[Category: Escherichia coli K-12]]
-[[Category: Cao, R.]]
+[[Category: Large Structures]]
-[[Category: Liu, Y L.]]
+[[Category: Cao R]]
-[[Category: Oldfield, E.]]
+[[Category: Liu Y-L]]
-[[Category: Alpha/beta]]
+[[Category: Oldfield E]]
-[[Category: Transferase-transferase inhibitor complex]]

3sh0: Difference between revisions

Latest revision as of 15:56, 14 March 2024

Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1065Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1065

Structural highlights

Function

See Also

References

Contents

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3sh0: Difference between revisions

Latest revision as of 15:56, 14 March 2024

Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1065Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1065

Structural highlights

Function

See Also

References

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