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New page: '''Unreleased structure''' The entry 3sh0 is ON HOLD Authors: Cao, R., Liu, Y.-L., Oldfield, E. Description: Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex... |
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==Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1065== | |||
<StructureSection load='3sh0' size='340' side='right'caption='[[3sh0]], [[Resolution|resolution]] 1.84Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3sh0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SH0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SH0 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.84Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAX:2-(DODECYLOXY)-6-HYDROXYBENZOIC+ACID'>SAX</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sh0 OCA], [https://pdbe.org/3sh0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sh0 RCSB], [https://www.ebi.ac.uk/pdbsum/3sh0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sh0 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/UPPS_ECOLI UPPS_ECOLI] Generates ditrans,octacis-undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) and farnesyl diphosphate (FPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.<ref>PMID:12756244</ref> | |||
==See Also== | |||
*[[Undecaprenyl pyrophosphate synthase 3D structures|Undecaprenyl pyrophosphate synthase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: Large Structures]] | |||
[[Category: Cao R]] | |||
[[Category: Liu Y-L]] | |||
[[Category: Oldfield E]] |
Latest revision as of 15:56, 14 March 2024
Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1065Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1065
Structural highlights
FunctionUPPS_ECOLI Generates ditrans,octacis-undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) and farnesyl diphosphate (FPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.[1] See AlsoReferences
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