3sb0: Difference between revisions

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-[[Image:3sb0.jpg|left|200px]]
-{{STRUCTURE_3sb0|  PDB=3sb0  |  SCENE=  }}
+==Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 4-(2-chloro-6-fluoro-3-methylphenyl)-2,4-dioxobutanoic acid inhibitor==
+<StructureSection load='3sb0' size='340' side='right'caption='[[3sb0]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3sb0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SB0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SB0 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.199&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=I93:4-(2-CHLORO-6-FLUORO-3-METHYLPHENYL)-2,4-DIOXOBUTANOIC+ACID'>I93</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sb0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sb0 OCA], [https://pdbe.org/3sb0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sb0 RCSB], [https://www.ebi.ac.uk/pdbsum/3sb0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sb0 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/MASZ_MYCTU MASZ_MYCTU] Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA (By similarity).[HAMAP-Rule:MF_00641]
-===Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 4-(2-chloro-6-fluoro-3-methylphenyl)-2,4-dioxobutanoic acid inhibitor===
+==See Also==
+*[[Malate synthase 3D structures|Malate synthase 3D structures]]
+__TOC__
-==About this Structure==
+</StructureSection>
-[[3sb0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SB0 OCA].
+[[Category: Large Structures]]
-[[Category: Malate synthase]]
 [[Category: Mycobacterium tuberculosis]]
-[[Category: Krieger, I V.]]
+[[Category: Krieger IV]]
-[[Category: Sacchettini, J C.]]
+[[Category: Sacchettini JC]]
-[[Category: Sun, Q.]]
+[[Category: Sun Q]]
-[[Category: XMTB, Mycobacterium Tuberculosis Structural Proteomics Project.]]
-[[Category: Inhibitor complex]]
-[[Category: Malate synthase]]
-[[Category: Mycobacterium tuberculosis structural proteomics project]]
-[[Category: Structural genomic]]
-[[Category: Transferase-transferase inhibitor complex]]
-[[Category: Xmtb]]