3s45: Difference between revisions

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[[Image:3s45.jpg|left|200px]]


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==wild-type HIV-2 protease with antiviral drug amprenavir==
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<StructureSection load='3s45' size='340' side='right'caption='[[3s45]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3s45]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_2 Human immunodeficiency virus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S45 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S45 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.51&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=478:{3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC+ACID+TETRAHYDRO-FURAN-3-YL+ESTER'>478</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_3s45|  PDB=3s45  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s45 OCA], [https://pdbe.org/3s45 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s45 RCSB], [https://www.ebi.ac.uk/pdbsum/3s45 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s45 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9W9R3_9HIV2 Q9W9R3_9HIV2]


===wild-type HIV-2 protease with antiviral drug amprenavir===
==See Also==
 
*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
 
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{{ABSTRACT_PUBMED_22238126}}
 
==About this Structure==
[[3s45]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_2 Human immunodeficiency virus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S45 OCA].
 
==Reference==
<ref group="xtra">PMID:022238126</ref><references group="xtra"/>
[[Category: HIV-2 retropepsin]]
[[Category: Human immunodeficiency virus 2]]
[[Category: Human immunodeficiency virus 2]]
[[Category: Tie, Y F.]]
[[Category: Large Structures]]
[[Category: Wang, Y F.]]
[[Category: Tie Y-F]]
[[Category: Weber, I T.]]
[[Category: Wang Y-F]]
[[Category: Amprenavir]]
[[Category: Weber IT]]
[[Category: Aspartic protease]]
[[Category: Drug resistance]]
[[Category: Hiv/aid]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Molecular recognition]]

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