3rhd: Difference between revisions
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<StructureSection load='3rhd' size='340' side='right'caption='[[3rhd]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='3rhd' size='340' side='right'caption='[[3rhd]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3rhd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3rhd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RHD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RHD FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | |||
<tr id=' | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rhd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rhd OCA], [https://pdbe.org/3rhd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rhd RCSB], [https://www.ebi.ac.uk/pdbsum/3rhd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rhd ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rhd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rhd OCA], [https://pdbe.org/3rhd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rhd RCSB], [https://www.ebi.ac.uk/pdbsum/3rhd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rhd ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/LADH_METJA LADH_METJA] Involved in F420 biosynthesis through the oxidation of lactaldehyde to lactate. The substrate preference order is propionaldehyde > DL-lactaldehyde, DL-glyceraldehyde > crotonaldehyde > glycolaldehyde > acetaldehyde, acrolein > formaldehyde. No activity was observed towards methylglyoxal or glyceraldehyde-3-phosphate. Has a preference for NAD over NADP. | |||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Methanocaldococcus jannaschii]] | ||
[[Category: | [[Category: Almo SC]] | ||
[[Category: | [[Category: Foti R]] | ||
[[Category: | [[Category: Garrett S]] | ||
[[Category: | [[Category: Malashkevich VN]] | ||
[[Category: Seidel | [[Category: Seidel R]] | ||
[[Category: Toro | [[Category: Toro R]] | ||
Latest revision as of 15:23, 14 March 2024
Crystal structure of glyceraldehyde-3-phosphate dehydrogenase GapN from Methanocaldococcus jannaschii DSM 2661 complexed with NADPCrystal structure of glyceraldehyde-3-phosphate dehydrogenase GapN from Methanocaldococcus jannaschii DSM 2661 complexed with NADP
Structural highlights
FunctionLADH_METJA Involved in F420 biosynthesis through the oxidation of lactaldehyde to lactate. The substrate preference order is propionaldehyde > DL-lactaldehyde, DL-glyceraldehyde > crotonaldehyde > glycolaldehyde > acetaldehyde, acrolein > formaldehyde. No activity was observed towards methylglyoxal or glyceraldehyde-3-phosphate. Has a preference for NAD over NADP. See Also |
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