3rel: Difference between revisions

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-[[Image:3rel.png|left|200px]]
-{{STRUCTURE_3rel|  PDB=3rel  |  SCENE=  }}
+==2.7 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b) Derivatized with Triamminechloroplatinum(II) Chloride==
+<StructureSection load='3rel' size='340' side='right'caption='[[3rel]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-===2.7 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b) Derivatized with Triamminechloroplatinum(II) Chloride===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3rel]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3REL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3REL FirstGlance]. <br>
-{{ABSTRACT_PUBMED_21724603}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PT:PLATINUM+(II)+ION'>PT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rel OCA], [https://pdbe.org/3rel PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rel RCSB], [https://www.ebi.ac.uk/pdbsum/3rel PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rel ProSAT]</span></td></tr>
-[[3rel]] is a 10 chain structure of [[Histone]] with sequence from [http://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3REL OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/H32_XENLA H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 ==See Also==
-*[[Histone|Histone]]
+*[[Histone 3D structures|Histone 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:021724603</ref><references group="xtra"/>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
 [[Category: Xenopus laevis]]
-[[Category: Davey, C A.]]
+[[Category: Davey CA]]
-[[Category: Wu, B.]]
+[[Category: Wu B]]
-[[Category: Nucleosome]]
-[[Category: Structural protein-dna complex]]