3qq6: Difference between revisions

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-[[Image:3qq6.png|left|200px]]
-<!--
+==The N-terminal DNA binding domain of SinR from Bacillus subtilis==
-The line below this paragraph, containing "STRUCTURE_3qq6", creates the "Structure Box" on the page.
+<StructureSection load='3qq6' size='340' side='right'caption='[[3qq6]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3qq6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QQ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QQ6 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qq6 OCA], [https://pdbe.org/3qq6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qq6 RCSB], [https://www.ebi.ac.uk/pdbsum/3qq6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qq6 ProSAT]</span></td></tr>
-{{STRUCTURE_3qq6|  PDB=3qq6  |  SCENE=  }}
+</table>
+== Function ==
-===The N-terminal DNA binding domain of SinR from Bacillus subtilis===
+[https://www.uniprot.org/uniprot/SINR_BACSU SINR_BACSU] Negative as well as positive regulator of alternate developmental processes that are induced at the end of vegetative growth in response to nutrient depletion. Binds to the alkaline protease (aprE) gene at two sites. Also acts as a repressor of the key sporulation gene spo0A. Negatively regulates transcription of the eps operon, which is responsible for the biosynthesis of an exopolysaccharide involved in biofilm formation; therefore it could govern the transition between a state in which bacteria swim or swarm and a state in which bacteria assemble into multicellular communities. Acts with Hpr as a corepressor of epr expression. Also negatively regulates transcription of the lutABC operon, which is required for lactate utilization. Repressor activity is regulated by SinI.<ref>PMID:1898931</ref> <ref>PMID:7642487</ref> <ref>PMID:15661000</ref> <ref>PMID:16923912</ref>
+== References ==
+<references/>
-<!--
+__TOC__
-The line below this paragraph, {{ABSTRACT_PUBMED_21708175}}, adds the Publication Abstract to the page
+</StructureSection>
-(as it appears on PubMed at http://www.pubmed.gov), where 21708175 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_21708175}}
-==About this Structure==
-[[3qq6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QQ6 OCA].
-==Reference==
-<ref group="xtra">PMID:021708175</ref><references group="xtra"/>
 [[Category: Bacillus subtilis]]
-[[Category: Colledge, V.]]
+[[Category: Large Structures]]
-[[Category: Dodson, E J.]]
+[[Category: Colledge V]]
-[[Category: Fogg, M J.]]
+[[Category: Dodson EJ]]
-[[Category: Levdikov, V M.]]
+[[Category: Fogg MJ]]
-[[Category: Wilkinson, A J.]]
+[[Category: Levdikov VM]]
-[[Category: Biofilm]]
+[[Category: Wilkinson AJ]]
-[[Category: Helix-turn-helix motif]]
-[[Category: Repressor]]
-[[Category: Sini]]
-[[Category: Transcription]]
-[[Category: Transcriptional regulator]]