3qmh: Difference between revisions

No edit summary
No edit summary
 
(4 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{STRUCTURE_3qmh|  PDB=3qmh  |  SCENE=  }}
===Structural Basis of Selective Binding of Non-Methylated CpG islands (DNA-TCGA) by the CXXC Domain of CFP1===
{{ABSTRACT_PUBMED_21407193}}


==Function==
==Structural Basis of Selective Binding of Non-Methylated CpG islands (DNA-TCGA) by the CXXC Domain of CFP1==
[[http://www.uniprot.org/uniprot/CXXC1_HUMAN CXXC1_HUMAN]] Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.<ref>PMID:21407193</ref> 
<StructureSection load='3qmh' size='340' side='right'caption='[[3qmh]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[3qmh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QMH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QMH FirstGlance]. <br>
[[3qmh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QMH OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qmh OCA], [https://pdbe.org/3qmh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qmh RCSB], [https://www.ebi.ac.uk/pdbsum/3qmh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qmh ProSAT]</span></td></tr>
<ref group="xtra">PMID:021407193</ref><references group="xtra"/><references/>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CXXC1_HUMAN CXXC1_HUMAN] Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.<ref>PMID:21407193</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Large Structures]]
[[Category: Bian, C.]]
[[Category: Arrowsmith CH]]
[[Category: Bountra, C.]]
[[Category: Bian C]]
[[Category: Edwards, A M.]]
[[Category: Bountra C]]
[[Category: MacKenzie, F.]]
[[Category: Edwards AM]]
[[Category: Min, J.]]
[[Category: MacKenzie F]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Min J]]
[[Category: Weigelt, J.]]
[[Category: Weigelt J]]
[[Category: Xu, C.]]
[[Category: Xu C]]
[[Category: Dna binding]]
[[Category: Dna binding protein-dna complex]]
[[Category: Sgc]]
[[Category: Structural genomics consortium]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA