3qlx: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:3qlx.jpg|left|200px]]
-<!--
+==Candida glabrata dihydrofolate reductase complexed with NADPH and 6-methyl-5-[(3R)-3-(3,4,5-trimethoxyphenyl)pent-1-yn-1-yl]pyrimidine-2,4-diamine (UCP112A)==
-The line below this paragraph, containing "STRUCTURE_3qlx", creates the "Structure Box" on the page.
+<StructureSection load='3qlx' size='340' side='right'caption='[[3qlx]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3qlx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_glabrata Candida glabrata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QLX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QLX FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.239&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=QLR:6-METHYL-5-[(3R)-3-(3,4,5-TRIMETHOXYPHENYL)PENT-1-YN-1-YL]PYRIMIDINE-2,4-DIAMINE'>QLR</scene></td></tr>
-{{STRUCTURE_3qlx|  PDB=3qlx  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qlx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qlx OCA], [https://pdbe.org/3qlx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qlx RCSB], [https://www.ebi.ac.uk/pdbsum/3qlx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qlx ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q6FPH0_CANGA Q6FPH0_CANGA]
-===Candida glabrata dihydrofolate reductase complexed with NADPH and 6-methyl-5-[(3R)-3-(3,4,5-trimethoxyphenyl)pent-1-yn-1-yl]pyrimidine-2,4-diamine (UCP112A)===
+==See Also==
+*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_21726415}}, adds the Publication Abstract to the page
+[[Category: Large Structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 21726415 is the PubMed ID number.
+[[Category: Anderson AC]]
--->
+[[Category: Bendel SD]]
-{{ABSTRACT_PUBMED_21726415}}
+[[Category: Paulsen JL]]
-==About this Structure==
-[[3qlx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Candida_glabrata Candida glabrata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QLX OCA].
-==Reference==
-<ref group="xtra">PMID:021726415</ref><references group="xtra"/>
-[[Category: Candida glabrata]]
-[[Category: Anderson, A C.]]
-[[Category: Bendel, S D.]]
-[[Category: Paulsen, J L.]]
-[[Category: Antifungal agent]]
-[[Category: Candida glabrata]]
-[[Category: Drug design]]
-[[Category: Enzyme inhibitor]]
-[[Category: Fungal protein]]
-[[Category: Model]]
-[[Category: Molecular structure]]
-[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
-[[Category: Structure-activity relationship]]
-[[Category: Tetrahydrofolate dehydrogenase]]