3qkt: Difference between revisions
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==Rad50 ABC-ATPase with adjacent coiled-coil region in complex with AMP-PNP== | |||
<StructureSection load='3qkt' size='340' side='right'caption='[[3qkt]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3qkt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QKT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QKT FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qkt OCA], [https://pdbe.org/3qkt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qkt RCSB], [https://www.ebi.ac.uk/pdbsum/3qkt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qkt ProSAT]</span></td></tr> | ||
[[3qkt]] is a 4 chain structure with sequence from [ | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/RAD50_PYRFU RAD50_PYRFU] Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and/or repositioning DNA ends into the Mre11 active site.[HAMAP-Rule:MF_00449] | |||
==See Also== | ==See Also== | ||
*[[ATPase|ATPase]] | *[[ATPase 3D structures|ATPase 3D structures]] | ||
__TOC__ | |||
</StructureSection> | |||
< | [[Category: Large Structures]] | ||
[[Category: Pyrococcus furiosus]] | [[Category: Pyrococcus furiosus]] | ||
[[Category: Arvai | [[Category: Arvai A]] | ||
[[Category: Moncalian | [[Category: Moncalian G]] | ||
[[Category: Tainer | [[Category: Tainer JA]] | ||
[[Category: Williams | [[Category: Williams GJ]] | ||
[[Category: Williams | [[Category: Williams RS]] | ||
Latest revision as of 14:49, 14 March 2024
Rad50 ABC-ATPase with adjacent coiled-coil region in complex with AMP-PNPRad50 ABC-ATPase with adjacent coiled-coil region in complex with AMP-PNP
Structural highlights
FunctionRAD50_PYRFU Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and/or repositioning DNA ends into the Mre11 active site.[HAMAP-Rule:MF_00449] See Also |
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