3qk3: Difference between revisions

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[[Image:3qk3.jpg|left|200px]]


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==Crystal structure of human beta-crystallin B3==
The line below this paragraph, containing "STRUCTURE_3qk3", creates the "Structure Box" on the page.
<StructureSection load='3qk3' size='340' side='right'caption='[[3qk3]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3qk3]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QK3 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_3qk3|  PDB=3qk3  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qk3 OCA], [https://pdbe.org/3qk3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qk3 RCSB], [https://www.ebi.ac.uk/pdbsum/3qk3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qk3 ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/CRBB3_HUMAN CRBB3_HUMAN] Non-syndromic congenital cataract. Cataract, congenital, nuclear, autosomal recessive 2 (CATCN2) [MIM:[https://omim.org/entry/609741 609741]: A congenital cataract affecting the central nucleus of the eye. Nucler cataracts are often not highly visually significant. The density of the opacities varies greatly from fine dots to a dense, white and chalk-like, central cataract. The condition is usually bilateral. Nuclear cataracts are often combined with opacified cortical fibers encircling the nuclear opacity, which are referred to as cortical riders. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:15914629</ref>  
== Function ==
[https://www.uniprot.org/uniprot/CRBB3_HUMAN CRBB3_HUMAN] Crystallins are the dominant structural components of the vertebrate eye lens.


===Crystal structure of human beta-crystallin B3===
==See Also==
 
*[[Crystallin 3D structures|Crystallin 3D structures]]
 
== References ==
==About this Structure==
<references/>
[[3qk3]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QK3 OCA].
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Large Structures]]
[[Category: Bountra, C.]]
[[Category: Arrowsmith CH]]
[[Category: Cocking, R.]]
[[Category: Bountra C]]
[[Category: Delft, F von.]]
[[Category: Cocking R]]
[[Category: Edwards, A.]]
[[Category: Edwards A]]
[[Category: Gileadi, C.]]
[[Category: Gileadi C]]
[[Category: Kavanagh, K.]]
[[Category: Kavanagh K]]
[[Category: Krojer, T.]]
[[Category: Krojer T]]
[[Category: Muniz, J.]]
[[Category: Muniz J]]
[[Category: Oppermann, U.]]
[[Category: Oppermann U]]
[[Category: Pike, A C.W.]]
[[Category: Pike ACW]]
[[Category: Pilka, E.]]
[[Category: Pilka E]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Vollmar M]]
[[Category: Vollmar, M.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Yue WW]]
[[Category: Yue, W W.]]
[[Category: Von Delft F]]

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