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{{STRUCTURE_3qas|  PDB=3qas  |  SCENE=  }}
===Structure of Undecaprenyl Diphosphate synthase===
{{ABSTRACT_PUBMED_21294851}}


==About this Structure==
==Structure of Undecaprenyl Diphosphate synthase==
[[3qas]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QAS OCA].  
<StructureSection load='3qas' size='340' side='right'caption='[[3qas]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3qas]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QAS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QAS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qas OCA], [https://pdbe.org/3qas PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qas RCSB], [https://www.ebi.ac.uk/pdbsum/3qas PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qas ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/UPPS_ECOLI UPPS_ECOLI] Generates ditrans,octacis-undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) and farnesyl diphosphate (FPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.<ref>PMID:12756244</ref>


==Reference==
==See Also==
<ref group="xtra">PMID:021294851</ref><references group="xtra"/><references/>
*[[Undecaprenyl pyrophosphate synthase 3D structures|Undecaprenyl pyrophosphate synthase 3D structures]]
[[Category: Di-trans,poly-cis-decaprenylcistransferase]]
== References ==
[[Category: Escherichia coli]]
<references/>
[[Category: Cao, R.]]
__TOC__
[[Category: Oldfield, E.]]
</StructureSection>
[[Category: Alpha-helix]]
[[Category: Escherichia coli K-12]]
[[Category: Isoprenoid biosynthesis]]
[[Category: Large Structures]]
[[Category: Transferase]]
[[Category: Cao R]]
[[Category: Oldfield E]]

Latest revision as of 14:38, 14 March 2024

Structure of Undecaprenyl Diphosphate synthaseStructure of Undecaprenyl Diphosphate synthase

Structural highlights

3qas is a 2 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.7Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

UPPS_ECOLI Generates ditrans,octacis-undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) and farnesyl diphosphate (FPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.[1]

See Also

References

  1. ↑ Chang SY, Ko TP, Liang PH, Wang AH. Catalytic mechanism revealed by the crystal structure of undecaprenyl pyrophosphate synthase in complex with sulfate, magnesium, and triton. J Biol Chem. 2003 Aug 1;278(31):29298-307. Epub 2003 May 19. PMID:12756244 doi:10.1074/jbc.M302687200

3qas, resolution 1.70Å

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