3q7u: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
 ==Structure of Mtb 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD) complexed with CTP==
-<StructureSection load='3q7u' size='340' side='right' caption='[[3q7u]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
+<StructureSection load='3q7u' size='340' side='right'caption='[[3q7u]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3q7u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q7U FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3q7u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q7U FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3okr|3okr]], [[3q80|3q80]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ispD, Rv3582c, MT3688, MTCY06G11.29c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q7u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7u OCA], [https://pdbe.org/3q7u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q7u RCSB], [https://www.ebi.ac.uk/pdbsum/3q7u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7u ProSAT]</span></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_4-phosphate_cytidylyltransferase 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.60 2.7.7.60] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q7u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q7u RCSB], [http://www.ebi.ac.uk/pdbsum/3q7u PDBsum]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/ISPD_MYCTU ISPD_MYCTU] Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity).
 ==See Also==
-*[[MEP cytidylyltransferase|MEP cytidylyltransferase]]
+*[[MEP cytidylyltransferase 3D structures|MEP cytidylyltransferase 3D structures]]
 __TOC__
 </StructureSection>
-[[Category: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase]]
+[[Category: Large Structures]]
-[[Category: Mycobacterium tuberculosis]]
+[[Category: Mycobacterium tuberculosis H37Rv]]
-[[Category: Bruning, J B.]]
+[[Category: Bruning JB]]
-[[Category: Ioerger, T R.]]
+[[Category: Ioerger TR]]
-[[Category: Reddy, M C.M.]]
+[[Category: Reddy MCM]]
-[[Category: Sacchettini, J C.]]
+[[Category: Sacchettini JC]]
-[[Category: TBSGC, TB Structural Genomics Consortium.]]
+[[Category: Thurman C]]
-[[Category: Thurman, C.]]
-[[Category: 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase]]
-[[Category: Rossmann fold]]
-[[Category: Tb structural genomics consortium]]
-[[Category: Tbsgc]]
-[[Category: Transferase]]