3q7q: Difference between revisions

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-[[Image:3q7q.jpg|left|200px]]
-<!--
+==Crystal Structure of Rad G-domain Q148A-GTP Analog Complex==
-The line below this paragraph, containing "STRUCTURE_3q7q", creates the "Structure Box" on the page.
+<StructureSection load='3q7q' size='340' side='right'caption='[[3q7q]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3q7q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q7Q FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-{{STRUCTURE_3q7q|  PDB=3q7q  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q7q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7q OCA], [https://pdbe.org/3q7q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q7q RCSB], [https://www.ebi.ac.uk/pdbsum/3q7q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7q ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/RAD_HUMAN RAD_HUMAN] May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.<ref>PMID:18056528</ref>
-===Crystal Structure of Rad G-domain Q148A-GTP Analog Complex===
+==See Also==
+*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_21903096}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 21903096 is the PubMed ID number.
+</StructureSection>
--->
-{{ABSTRACT_PUBMED_21903096}}
-==About this Structure==
-[[3q7q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7Q OCA].
-==Reference==
-<ref group="xtra">PMID:021903096</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Hirsch, J A.]]
+[[Category: Large Structures]]
-[[Category: Navon-Perry, L.]]
+[[Category: Hirsch JA]]
-[[Category: Sasson, Y.]]
+[[Category: Navon-Perry L]]
-[[Category: Cav2 beta]]
+[[Category: Sasson Y]]
-[[Category: G-domain]]
-[[Category: G-protein]]
-[[Category: Signaling protein]]