1c0n: Difference between revisions

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-[[Image:1c0n.png|left|200px]]
-{{STRUCTURE_1c0n|  PDB=1c0n  |  SCENE=  }}
+==CSDB PROTEIN, NIFS HOMOLOGUE==
+<StructureSection load='1c0n' size='340' side='right'caption='[[1c0n]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1c0n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C0N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C0N FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c0n OCA], [https://pdbe.org/1c0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c0n RCSB], [https://www.ebi.ac.uk/pdbsum/1c0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c0n ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SUFS_ECOLI SUFS_ECOLI] Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo.<ref>PMID:10829016</ref> <ref>PMID:12089140</ref> <ref>PMID:11997471</ref> <ref>PMID:12876288</ref> <ref>PMID:12941942</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c0/1c0n_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1c0n ConSurf].
+<div style="clear:both"></div>
-===CSDB PROTEIN, NIFS HOMOLOGUE===
+==See Also==
+*[[Selenocysteine lyase|Selenocysteine lyase]]
-{{ABSTRACT_PUBMED_10684605}}
+== References ==
+<references/>
-==About this Structure==
+__TOC__
-[[1c0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C0N OCA].
+</StructureSection>
-==Reference==
-<ref group="xtra">PMID:010684605</ref><references group="xtra"/>
 [[Category: Escherichia coli]]
-[[Category: Esaki, N.]]
+[[Category: Large Structures]]
-[[Category: Fujii, T.]]
+[[Category: Esaki N]]
-[[Category: Hata, Y.]]
+[[Category: Fujii T]]
-[[Category: Kurihara, T.]]
+[[Category: Hata Y]]
-[[Category: Maeda, M.]]
+[[Category: Kurihara T]]
-[[Category: Mihara, H.]]
+[[Category: Maeda M]]
-[[Category: Alpha/beta fold]]
+[[Category: Mihara H]]
-[[Category: Lyase]]