1ah5: Difference between revisions

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-{{Seed}}
-[[Image:1ah5.png|left|200px]]
-<!--
+==REDUCED FORM SELENOMETHIONINE-LABELLED HYDROXYMETHYLBILANE SYNTHASE DETERMINED BY MAD==
-The line below this paragraph, containing "STRUCTURE_1ah5", creates the "Structure Box" on the page.
+<StructureSection load='1ah5' size='340' side='right'caption='[[1ah5]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1ah5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AH5 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPM:3-[5-{[3-(2-CARBOXYETHYL)-4-(CARBOXYMETHYL)-5-METHYL-1H-PYRROL-2-YL]METHYL}-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC+ACID'>DPM</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-{{STRUCTURE_1ah5|  PDB=1ah5  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ah5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ah5 OCA], [https://pdbe.org/1ah5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ah5 RCSB], [https://www.ebi.ac.uk/pdbsum/1ah5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ah5 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/HEM3_ECOLI HEM3_ECOLI] Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.[HAMAP-Rule:MF_00260]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ah/1ah5_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ah5 ConSurf].
+<div style="clear:both"></div>
-===REDUCED FORM SELENOMETHIONINE-LABELLED HYDROXYMETHYLBILANE SYNTHASE DETERMINED BY MAD===
+==See Also==
+*[[Porphobilinogen Deaminase|Porphobilinogen Deaminase]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_10089459}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 10089459 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_10089459}}
-==About this Structure==
-AH5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AH5 OCA].
-==Reference==
-Determination of the structure of seleno-methionine-labelled hydroxymethylbilane synthase in its active form by multi-wavelength anomalous dispersion., Hadener A, Matzinger PK, Battersby AR, McSweeney S, Thompson AW, Hammersley AP, Harrop SJ, Cassetta A, Deacon A, Hunter WN, Nieh YP, Raftery J, Hunter N, Helliwell JR, Acta Crystallogr D Biol Crystallogr. 1999 Mar;55(Pt 3):631-43. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10089459 10089459]
 [[Category: Escherichia coli]]
-[[Category: Hydroxymethylbilane synthase]]
+[[Category: Large Structures]]
-[[Category: Single protein]]
+[[Category: Cassetta A]]
-[[Category: Cassetta, A.]]
+[[Category: Harrop SJ]]
-[[Category: Harrop, S J.]]
+[[Category: Helliwell JR]]
-[[Category: Helliwell, J R.]]
+[[Category: Nieh YP]]
-[[Category: Nieh, Y P.]]
-[[Category: All alpha/beta]]
-[[Category: Biosynthesis of linear tetrapyrrole]]
-[[Category: Lyase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 16:50:21 2008''