6ufm: Difference between revisions

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 <StructureSection load='6ufm' size='340' side='right'caption='[[6ufm]], [[Resolution|resolution]] 2.82&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6ufm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UFM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UFM FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6ufm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis Mycolicibacterium smegmatis] and [https://en.wikipedia.org/wiki/Nocardia_farcinica Nocardia farcinica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UFM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UFM FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.82&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ufm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ufm OCA], [http://pdbe.org/6ufm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ufm RCSB], [http://www.ebi.ac.uk/pdbsum/6ufm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ufm ProSAT]</span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ufm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ufm OCA], [https://pdbe.org/6ufm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ufm RCSB], [https://www.ebi.ac.uk/pdbsum/6ufm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ufm ProSAT]</span></td></tr>
 </table>
-<div style="background-color:#fffaf0;">
-== Publication Abstract from PubMed ==
-T-box riboswitches are modular bacterial noncoding RNAs that sense and regulate amino acid availability through direct interactions with tRNAs. Between the 5' anticodon-binding stem I domain and the 3' amino acid sensing domains of most T-boxes lies the stem II domain of unknown structure and function. Here, we report a 2.8-A cocrystal structure of the Nocardia farcinica ileS T-box in complex with its cognate tRNA(Ile). The structure reveals a perpendicularly arranged ultrashort stem I containing a K-turn and an elongated stem II bearing an S-turn. Both stems rest against a compact pseudoknot, dock via an extended ribose zipper and jointly create a binding groove specific to the anticodon of its cognate tRNA. Contrary to proposed distal contacts to the tRNA elbow region, stem II locally reinforces the codon-anticodon interactions between stem I and tRNA, achieving low-nanomolar affinity. This study illustrates how mRNA junctions can create specific binding sites for interacting RNAs of prescribed sequence and structure.
-High-affinity recognition of specific tRNAs by an mRNA anticodon-binding groove.,Suddala KC, Zhang J Nat Struct Mol Biol. 2019 Dec;26(12):1114-1122. doi: 10.1038/s41594-019-0335-6., Epub 2019 Dec 2. PMID:31792448<ref>PMID:31792448</ref>
+==See Also==
+*[[Riboswitch 3D structures|Riboswitch 3D structures]]
-From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-</div>
-<div class="pdbe-citations 6ufm" style="background-color:#fffaf0;"></div>
-== References ==
-<references/>
 __TOC__
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Suddala, K C]]
+[[Category: Mycolicibacterium smegmatis]]
-[[Category: Zhang, J]]
+[[Category: Nocardia farcinica]]
-[[Category: Complex]]
+[[Category: Suddala KC]]
-[[Category: Rna]]
+[[Category: Zhang J]]