6mrg: Difference between revisions

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-'''Unreleased structure'''
-The entry 6mrg is ON HOLD
+==FAAH bound to non covalent inhibitor==
+<StructureSection load='6mrg' size='340' side='right'caption='[[6mrg]], [[Resolution|resolution]] 2.77&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6mrg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MRG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6MRG FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.77&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JXV:(1R)-2-{[6-(2,3-dihydro-1,4-benzodioxin-6-yl)pyrimidin-4-yl]amino}-1-phenylethan-1-ol'>JXV</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6mrg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mrg OCA], [https://pdbe.org/6mrg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6mrg RCSB], [https://www.ebi.ac.uk/pdbsum/6mrg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6mrg ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/FAAH1_RAT FAAH1_RAT] Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates (By similarity).
-Authors: Saha, A., Shih, A., Mirzadegan, T., Seierstad, M.
+==See Also==
+*[[Fatty acid amide hydrolase|Fatty acid amide hydrolase]]
-Description: FAAH bound to non covalent inhibitor
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Seierstad, M]]
+[[Category: Large Structures]]
-[[Category: Mirzadegan, T]]
+[[Category: Rattus norvegicus]]
-[[Category: Saha, A]]
+[[Category: Mirzadegan T]]
-[[Category: Shih, A]]
+[[Category: Saha A]]
+[[Category: Seierstad M]]
+[[Category: Shih A]]