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==Crystal structure of Plasmodium falciparum topoisomerase II DNA-binding, cleavage and re-ligation domain== | ==Crystal structure of Plasmodium falciparum topoisomerase II DNA-binding, cleavage and re-ligation domain== | ||
<StructureSection load='6ca8' size='340' side='right' caption='[[6ca8]], [[Resolution|resolution]] 2.33Å' scene=''> | <StructureSection load='6ca8' size='340' side='right'caption='[[6ca8]], [[Resolution|resolution]] 2.33Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6ca8]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[6ca8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CA8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CA8 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.331Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ca8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ca8 OCA], [https://pdbe.org/6ca8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ca8 RCSB], [https://www.ebi.ac.uk/pdbsum/6ca8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ca8 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/Q7Z2D0_PLAFA Q7Z2D0_PLAFA] Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.[RuleBase:RU362094] | ||
==See Also== | |||
*[[Gyrase 3D Structures|Gyrase 3D Structures]] | |||
*[[Topoisomerase 3D structures|Topoisomerase 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Plasmodium falciparum]] | ||
[[Category: | [[Category: Kandavelu P]] | ||
[[Category: Kumar S]] | |||
[[Category: | [[Category: Rathod PK]] | ||
[[Category: | |||
Latest revision as of 17:27, 13 March 2024
Crystal structure of Plasmodium falciparum topoisomerase II DNA-binding, cleavage and re-ligation domainCrystal structure of Plasmodium falciparum topoisomerase II DNA-binding, cleavage and re-ligation domain
Structural highlights
FunctionQ7Z2D0_PLAFA Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.[RuleBase:RU362094] See Also |
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