6bvr: Difference between revisions

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'''Unreleased structure'''


The entry 6bvr is ON HOLD
==Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase I142A from Cupriavidus metallidurans==
<StructureSection load='6bvr' size='340' side='right'caption='[[6bvr]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6bvr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cupriavidus_metallidurans Cupriavidus metallidurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BVR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BVR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bvr OCA], [https://pdbe.org/6bvr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bvr RCSB], [https://www.ebi.ac.uk/pdbsum/6bvr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bvr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/3HAO_CUPMC 3HAO_CUPMC] Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.[HAMAP-Rule:MF_00825]<ref>PMID:15909977</ref>


Authors: Yang, Y., Liu, F., Liu, A.
==See Also==
 
*[[Dioxygenase 3D structures|Dioxygenase 3D structures]]
Description: Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase I142A from Cupriavidus metallidurans
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Liu, F]]
__TOC__
[[Category: Yang, Y]]
</StructureSection>
[[Category: Liu, A]]
[[Category: Cupriavidus metallidurans]]
[[Category: Large Structures]]
[[Category: Liu A]]
[[Category: Liu F]]
[[Category: Yang Y]]

Latest revision as of 17:24, 13 March 2024

Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase I142A from Cupriavidus metalliduransCrystal structure of 3-hydroxyanthranilate-3,4-dioxygenase I142A from Cupriavidus metallidurans

Structural highlights

6bvr is a 1 chain structure with sequence from Cupriavidus metallidurans. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

3HAO_CUPMC Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.[HAMAP-Rule:MF_00825][1]

See Also

References

  1. ↑ Colabroy KL, Zhai H, Li T, Ge Y, Zhang Y, Liu A, Ealick SE, McLafferty FW, Begley TP. The mechanism of inactivation of 3-hydroxyanthranilate-3,4-dioxygenase by 4-chloro-3-hydroxyanthranilate. Biochemistry. 2005 May 31;44(21):7623-31. PMID:15909977 doi:http://dx.doi.org/10.1021/bi0473455

6bvr, resolution 1.90Å

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