6bp8: Difference between revisions
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==Recombinant major vault protein [Rattus norvegicus] structure in solution: conformation 1== | |||
<SX load='6bp8' size='340' side='right' viewer='molstar' caption='[[6bp8]], [[Resolution|resolution]] 4.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6bp8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BP8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BP8 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.9Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bp8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bp8 OCA], [https://pdbe.org/6bp8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bp8 RCSB], [https://www.ebi.ac.uk/pdbsum/6bp8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bp8 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MVP_RAT MVP_RAT] Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (By similarity). | |||
__TOC__ | |||
</SX> | |||
[[Category: Large Structures]] | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Ding K]] | |||
[[Category: Kickhoefer VA]] | |||
[[Category: Lai M]] | |||
[[Category: Mrazek J]] | |||
[[Category: Ng HL]] | |||
[[Category: Rome LH]] | |||
[[Category: Yang OO]] | |||
[[Category: Zhang X]] | |||
[[Category: Zhou ZH]] | |||
Latest revision as of 17:23, 13 March 2024
Recombinant major vault protein [Rattus norvegicus] structure in solution: conformation 1Recombinant major vault protein [Rattus norvegicus] structure in solution: conformation 1
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