6b8f: Difference between revisions
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New page: '''Unreleased structure''' The entry 6b8f is ON HOLD until Paper Publication Authors: Zhang, L., Bailey, J.B., Subramanian, R., Tezcan, F.A. Description: Contracted Human Heavy-Chain F... |
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==Contracted Human Heavy-Chain Ferritin Crystal-Hydrogel Hybrid== | |||
<StructureSection load='6b8f' size='340' side='right'caption='[[6b8f]], [[Resolution|resolution]] 1.06Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6b8f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B8F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6B8F FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.06Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6b8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b8f OCA], [https://pdbe.org/6b8f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6b8f RCSB], [https://www.ebi.ac.uk/pdbsum/6b8f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6b8f ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). | |||
==See Also== | |||
*[[Ferritin 3D structures|Ferritin 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Bailey JB]] | ||
[[Category: | [[Category: Subramanian R]] | ||
[[Category: Tezcan FA]] | |||
[[Category: Zhang L]] | |||
Latest revision as of 17:20, 13 March 2024
Contracted Human Heavy-Chain Ferritin Crystal-Hydrogel HybridContracted Human Heavy-Chain Ferritin Crystal-Hydrogel Hybrid
Structural highlights
FunctionFRIH_HUMAN Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). See Also |
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