6b5j: Difference between revisions

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'''Unreleased structure'''


The entry 6b5j is ON HOLD
==TNNI3K complexed with a 4,6-diaminopyrimidine==
<StructureSection load='6b5j' size='340' side='right'caption='[[6b5j]], [[Resolution|resolution]] 2.97&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6b5j]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B5J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6B5J FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.97&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CV4:N-methyl-3-[(6-{[4-(trifluoromethyl)phenyl]amino}pyrimidin-4-yl)amino]benzene-1-sulfonamide'>CV4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6b5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b5j OCA], [https://pdbe.org/6b5j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6b5j RCSB], [https://www.ebi.ac.uk/pdbsum/6b5j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6b5j ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/TNI3K_HUMAN TNI3K_HUMAN] The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/TNI3K_HUMAN TNI3K_HUMAN] May play a role in cardiac physiology.<ref>PMID:12721663</ref>


Authors: Shewchuk, L.M., Philp, J.
==See Also==
 
*[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]]
Description: TNNI3K complexed with a 4,6-diaminopyrimidine
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Shewchuk, L.M]]
__TOC__
[[Category: Philp, J]]
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Philp J]]
[[Category: Shewchuk LM]]

Latest revision as of 17:20, 13 March 2024

TNNI3K complexed with a 4,6-diaminopyrimidineTNNI3K complexed with a 4,6-diaminopyrimidine

Structural highlights

6b5j is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.97Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

TNI3K_HUMAN The disease is caused by mutations affecting the gene represented in this entry.

Function

TNI3K_HUMAN May play a role in cardiac physiology.[1]

See Also

References

  1. ↑ Zhao Y, Meng XM, Wei YJ, Zhao XW, Liu DQ, Cao HQ, Liew CC, Ding JF. Cloning and characterization of a novel cardiac-specific kinase that interacts specifically with cardiac troponin I. J Mol Med. 2003 May;81(5):297-304. Epub 2003 Apr 30. PMID:12721663 doi:http://dx.doi.org/10.1007/s00109-003-0427-x

6b5j, resolution 2.97Å

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OCA
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