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==Naegleria fowleri CYP51-fluconazole complex==
==Naegleria fowleri CYP51-fluconazole complex==
<StructureSection load='6ay4' size='340' side='right' caption='[[6ay4]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='6ay4' size='340' side='right'caption='[[6ay4]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6ay4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AY4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AY4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6ay4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Naegleria_fowleri Naegleria fowleri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AY4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AY4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=TPF:2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL'>TPF</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5tl8|5tl8]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=TPF:2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL'>TPF</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ay4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ay4 OCA], [http://pdbe.org/6ay4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ay4 RCSB], [http://www.ebi.ac.uk/pdbsum/6ay4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ay4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ay4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ay4 OCA], [https://pdbe.org/6ay4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ay4 RCSB], [https://www.ebi.ac.uk/pdbsum/6ay4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ay4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A2H4A2U9_NAEFO A0A2H4A2U9_NAEFO]
==See Also==
*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Abagyan, R]]
[[Category: Large Structures]]
[[Category: Aksenov, A]]
[[Category: Naegleria fowleri]]
[[Category: Calvet, C M]]
[[Category: Abagyan R]]
[[Category: Debnath, A]]
[[Category: Aksenov A]]
[[Category: Jennings, G]]
[[Category: Calvet CM]]
[[Category: Luth, M]]
[[Category: Debnath A]]
[[Category: McKerrow, J H]]
[[Category: Jennings G]]
[[Category: Nes, W D]]
[[Category: Luth M]]
[[Category: Podust, L M]]
[[Category: McKerrow JH]]
[[Category: Zhou, W]]
[[Category: Nes WD]]
[[Category: Cyp51]]
[[Category: Podust LM]]
[[Category: Oxidoreductase]]
[[Category: Zhou W]]
[[Category: Sterol 14alpha-demethylase]]

Latest revision as of 17:19, 13 March 2024

Naegleria fowleri CYP51-fluconazole complexNaegleria fowleri CYP51-fluconazole complex

Structural highlights

6ay4 is a 1 chain structure with sequence from Naegleria fowleri. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.7Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

A0A2H4A2U9_NAEFO

See Also

6ay4, resolution 2.70Å

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