5vsr: Difference between revisions

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New page: '''Unreleased structure''' The entry 5vsr is ON HOLD Authors: Cao, M.-J., Zhang, Y.-L., Liu, X., Huang, H., Zhou, X.E., Wang, W.-L., Zeng, A., Zhao, C.-Z., Si, T., Du, J.-M., Wu, W.-W.,...
 
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'''Unreleased structure'''


The entry 5vsr is ON HOLD
==ABA-mimicking ligand AMF4 in complex with ABA receptor PYL2 and PP2C HAB1==
<StructureSection load='5vsr' size='340' side='right'caption='[[5vsr]], [[Resolution|resolution]] 2.62&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5vsr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VSR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VSR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.618&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AF0:N-(2-oxo-1-propyl-1,2,3,4-tetrahydroquinolin-6-yl)-1-(2,3,5,6-tetrafluoro-4-methylphenyl)methanesulfonamide'>AF0</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vsr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vsr OCA], [https://pdbe.org/5vsr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vsr RCSB], [https://www.ebi.ac.uk/pdbsum/5vsr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vsr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PYL2_ARATH PYL2_ARATH] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.<ref>PMID:19898420</ref> <ref>PMID:19893533</ref>


Authors: Cao, M.-J., Zhang, Y.-L., Liu, X., Huang, H., Zhou, X.E., Wang, W.-L., Zeng, A., Zhao, C.-Z., Si, T., Du, J.-M., Wu, W.-W., Wang, F.-X., Xu, H.X., Zhu, J.-K.
==See Also==
 
*[[Abscisic acid receptor 3D structures|Abscisic acid receptor 3D structures]]
Description: ABA-mimicking ligand AMF4 in complex with ABA receptor PYL2 and PP2C HAB1
*[[Protein phosphatase 3D structures|Protein phosphatase 3D structures]]
[[Category: Unreleased Structures]]
== References ==
[[Category: Zhou, X.E]]
<references/>
[[Category: Wu, W.-W]]
__TOC__
[[Category: Du, J.-M]]
</StructureSection>
[[Category: Cao, M.-J]]
[[Category: Arabidopsis thaliana]]
[[Category: Si, T]]
[[Category: Large Structures]]
[[Category: Zeng, A]]
[[Category: Cao M-J]]
[[Category: Huang, H]]
[[Category: Du J-M]]
[[Category: Zhao, C.-Z]]
[[Category: Huang H]]
[[Category: Liu, X]]
[[Category: Liu X]]
[[Category: Wang, F.-X]]
[[Category: Si T]]
[[Category: Zhang, Y.-L]]
[[Category: Wang F-X]]
[[Category: Xu, H.X]]
[[Category: Wang W-L]]
[[Category: Wang, W.-L]]
[[Category: Wu W-W]]
[[Category: Zhu, J.-K]]
[[Category: Xu HX]]
[[Category: Zeng A]]
[[Category: Zhang Y-L]]
[[Category: Zhao C-Z]]
[[Category: Zhou XE]]
[[Category: Zhu J-K]]

Latest revision as of 17:12, 13 March 2024

ABA-mimicking ligand AMF4 in complex with ABA receptor PYL2 and PP2C HAB1ABA-mimicking ligand AMF4 in complex with ABA receptor PYL2 and PP2C HAB1

Structural highlights

5vsr is a 2 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.618Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PYL2_ARATH Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.[1] [2]

See Also

References

  1. ↑ Melcher K, Ng LM, Zhou XE, Soon FF, Xu Y, Suino-Powell KM, Park SY, Weiner JJ, Fujii H, Chinnusamy V, Kovach A, Li J, Wang Y, Li J, Peterson FC, Jensen DR, Yong EL, Volkman BF, Cutler SR, Zhu JK, Xu HE. A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors. Nature. 2009 Dec 3;462(7273):602-8. PMID:19898420 doi:10.1038/nature08613
  2. ↑ Yin P, Fan H, Hao Q, Yuan X, Wu D, Pang Y, Yan C, Li W, Wang J, Yan N. Structural insights into the mechanism of abscisic acid signaling by PYL proteins. Nat Struct Mol Biol. 2009 Dec;16(12):1230-6. Epub 2009 Nov 5. PMID:19893533 doi:10.1038/nsmb.1730

5vsr, resolution 2.62Å

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