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==2009 H1N1 PA Endonuclease in complex with RO-7 and Magnesium==
==2009 H1N1 PA Endonuclease in complex with RO-7 and Magnesium==
<StructureSection load='5vrj' size='340' side='right' caption='[[5vrj]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='5vrj' size='340' side='right'caption='[[5vrj]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5vrj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VRJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VRJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[5vrj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/California/04/2009(H1N1)) Influenza A virus (A/California/04/2009(H1N1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VRJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VRJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=R07:1-[(11S)-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-5-hydroxy-3-[(2R)-1,1,1-trifluoropropan-2-yl]-2,3-dihydro-1H-pyrido[2,1-f][1,2,4]triazine-4,6-dione'>R07</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.302&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5vp8|5vp8]], [[5vpt|5vpt]], [[5vpx|5vpx]], [[5vqn|5vqn]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=R07:1-[(11S)-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-5-hydroxy-3-[(2R)-1,1,1-trifluoropropan-2-yl]-2,3-dihydro-1H-pyrido[2,1-f][1,2,4]triazine-4,6-dione'>R07</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vrj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vrj OCA], [http://pdbe.org/5vrj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vrj RCSB], [http://www.ebi.ac.uk/pdbsum/5vrj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vrj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vrj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vrj OCA], [https://pdbe.org/5vrj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vrj RCSB], [https://www.ebi.ac.uk/pdbsum/5vrj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vrj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/C3W5S0_I09A0 C3W5S0_I09A0]
==See Also==
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Kumar, G]]
[[Category: Large Structures]]
[[Category: White, S W]]
[[Category: Kumar G]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: White SW]]
[[Category: Nuclease influenza inhibitor resistance]]

Latest revision as of 17:12, 13 March 2024

2009 H1N1 PA Endonuclease in complex with RO-7 and Magnesium2009 H1N1 PA Endonuclease in complex with RO-7 and Magnesium

Structural highlights

5vrj is a 1 chain structure with sequence from Influenza A virus (A/California/04/2009(H1N1)). Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.302Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

C3W5S0_I09A0

See Also

5vrj, resolution 2.30Å

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