5uyp: Difference between revisions
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New page: '''Unreleased structure''' The entry 5uyp is ON HOLD Authors: Description: Category: Unreleased Structures |
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==70S ribosome bound with near-cognate ternary complex base-paired to A site codon, open 30S (Structure II-nc)== | |||
<SX load='5uyp' size='340' side='right' viewer='molstar' caption='[[5uyp]], [[Resolution|resolution]] 3.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5uyp]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UYP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UYP FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.9Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FME:N-FORMYLMETHIONINE'>FME</scene>, <scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=U8U:5-METHYLAMINOMETHYL-2-THIOURIDINE-5-MONOPHOSPHATE'>U8U</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5uyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uyp OCA], [https://pdbe.org/5uyp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5uyp RCSB], [https://www.ebi.ac.uk/pdbsum/5uyp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5uyp ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RL2_ECOLI RL2_ECOLI] One of the primary rRNA binding proteins. Located near the base of the L1 stalk, it is probably also mobile. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is highly controversial.[HAMAP-Rule:MF_01320_B] In the E.coli 70S ribosome in the initiation state it has been modeled to make several contacts with the 16S rRNA (forming bridge B7b, PubMed:12809609); these contacts are broken in the model with bound EF-G.[HAMAP-Rule:MF_01320_B] | |||
==See Also== | |||
*[[Elongation factor 3D structures|Elongation factor 3D structures]] | |||
*[[Ribosome 3D structures|Ribosome 3D structures]] | |||
[[Category: | __TOC__ | ||
</SX> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: Large Structures]] | |||
[[Category: Demo G]] | |||
[[Category: Grigorieff N]] | |||
[[Category: Korostelev AA]] | |||
[[Category: Loveland AB]] | |||
Latest revision as of 17:09, 13 March 2024
70S ribosome bound with near-cognate ternary complex base-paired to A site codon, open 30S (Structure II-nc)70S ribosome bound with near-cognate ternary complex base-paired to A site codon, open 30S (Structure II-nc)
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