3b0f: Difference between revisions

<StructureSection load='3b0f' size='340' side='right'caption='[[3b0f]], [[Resolution|resolution]] 1.40&Aring;' scene=''>

<table><tr><td colspan='2'>[[3b0f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B0F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B0F FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b0f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b0f OCA], [https://pdbe.org/3b0f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b0f RCSB], [https://www.ebi.ac.uk/pdbsum/3b0f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b0f ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/SQSTM_MOUSE SQSTM_MOUSE] Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures). Links ALIS to the autophagic machinery via direct interaction with MAP1 LC3 family members. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. Adapter that mediates the interaction between TRAF6 and CYLD.<ref>PMID:14960283</ref> <ref>PMID:18382763</ref>  

[[Category: Arita K]]

[[Category: Hasegawa J]]

[[Category: Isogai S]]

[[Category: Komatsu M]]

[[Category: Morimoto D]]

[[Category: Shirakawa M]]

[[Category: Sou Y]]

[[Category: Tanaka K]]

[[Category: Tenno T]]

[[Category: Tochio H]]

[[Category: Unzai S]]