3ajp: Difference between revisions

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-[[Image:3ajp.png|left|200px]]
-{{STRUCTURE_3ajp|  PDB=3ajp  |  SCENE=  }}
+==Crystal structure of human H ferritin E140A mutant==
+<StructureSection load='3ajp' size='340' side='right'caption='[[3ajp]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-===Crystal structure of human H ferritin E140A mutant===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3ajp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AJP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AJP FirstGlance]. <br>
-{{ABSTRACT_PUBMED_20705053}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.901&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ajp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ajp OCA], [https://pdbe.org/3ajp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ajp RCSB], [https://www.ebi.ac.uk/pdbsum/3ajp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ajp ProSAT]</span></td></tr>
-[[3ajp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AJP OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aj/3ajp_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ajp ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Ferritin|Ferritin]]
+*[[Ferritin 3D structures|Ferritin 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:020705053</ref><references group="xtra"/>
-[[Category: Ferroxidase]]
 [[Category: Homo sapiens]]
-[[Category: Masuda, T.]]
+[[Category: Large Structures]]
-[[Category: Mikami, B.]]
+[[Category: Masuda T]]
-[[Category: 4-helix bundle]]
+[[Category: Mikami B]]
-[[Category: Oxidoreductase]]