3a06: Difference between revisions

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[[Image:3a06.jpg|left|200px]]


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==Crystal structure of DXR from Thermooga maritia, in complex with fosmidomycin and NADPH==
The line below this paragraph, containing "STRUCTURE_3a06", creates the "Structure Box" on the page.
<StructureSection load='3a06' size='340' side='right'caption='[[3a06]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3a06]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A06 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FOM:3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC+ACID'>FOM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
{{STRUCTURE_3a06| PDB=3a06 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a06 OCA], [https://pdbe.org/3a06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a06 RCSB], [https://www.ebi.ac.uk/pdbsum/3a06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a06 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DXR_THEMA DXR_THEMA] Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a0/3a06_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3a06 ConSurf].
<div style="clear:both"></div>


===Crystal structure of DXR from Thermooga maritia, in complex with fosmidomycin and NADPH===
==See Also==
 
*[[DXP reductoisomerase 3D Structures|DXP reductoisomerase 3D Structures]]
 
__TOC__
==About this Structure==
</StructureSection>
3A06 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A06 OCA].
[[Category: Large Structures]]
[[Category: 1-deoxy-D-xylulose-5-phosphate reductoisomerase]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
[[Category: Noguchi, K.]]
[[Category: Noguchi K]]
[[Category: Ohsawa, K.]]
[[Category: Ohsawa K]]
[[Category: Ohtaki, A.]]
[[Category: Ohtaki A]]
[[Category: Sasaki, Y.]]
[[Category: Sasaki Y]]
[[Category: Takenoya, M.]]
[[Category: Takenoya M]]
[[Category: Yajima, S.]]
[[Category: Yajima S]]
[[Category: Yohda, M.]]
[[Category: Yohda M]]
[[Category: Isoprene biosynthesis]]
[[Category: Mep pathway]]
[[Category: Metal-binding]]
[[Category: Nadp]]
[[Category: Oxidoreductase]]
[[Category: Reductoisomerase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 17 09:38:16 2010''

Latest revision as of 16:59, 13 March 2024

Crystal structure of DXR from Thermooga maritia, in complex with fosmidomycin and NADPHCrystal structure of DXR from Thermooga maritia, in complex with fosmidomycin and NADPH

Structural highlights

3a06 is a 2 chain structure with sequence from Thermotoga maritima. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DXR_THEMA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3a06, resolution 2.00Å

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