2zrv: Difference between revisions

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-[[Image:2zrv.png|left|200px]]
-<!--
+==Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with reduced FMN.==
-The line below this paragraph, containing "STRUCTURE_2zrv", creates the "Structure Box" on the page.
+<StructureSection load='2zrv' size='340' side='right'caption='[[2zrv]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2zrv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_shibatae Saccharolobus shibatae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZRV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZRV FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FNR:1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL'>FNR</scene></td></tr>
-{{STRUCTURE_2zrv|  PDB=2zrv  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zrv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zrv OCA], [https://pdbe.org/2zrv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zrv RCSB], [https://www.ebi.ac.uk/pdbsum/2zrv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zrv ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/IDI2_SACSH IDI2_SACSH] Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).[HAMAP-Rule:MF_00354]<ref>PMID:19158086</ref> <ref>PMID:22158896</ref> <ref>PMID:22505674</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zr/2zrv_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zrv ConSurf].
+<div style="clear:both"></div>
-===Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with reduced FMN.===
+==See Also==
+*[[Isopentenyl-diphosphate delta-isomerase|Isopentenyl-diphosphate delta-isomerase]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_19158086}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 19158086 is the PubMed ID number.
+</StructureSection>
--->
+[[Category: Large Structures]]
-{{ABSTRACT_PUBMED_19158086}}
+[[Category: Saccharolobus shibatae]]
+[[Category: Hemmi H]]
-==About this Structure==
+[[Category: Ikeda Y]]
-[[2zrv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_shibatae Sulfolobus shibatae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZRV OCA].
+[[Category: Kusunoki M]]
+[[Category: Nakayama T]]
-==Reference==
+[[Category: Nishino T]]
-<ref group="xtra">PMID:019158086</ref><references group="xtra"/>
+[[Category: Sekiguchi S]]
-[[Category: Isopentenyl-diphosphate Delta-isomerase]]
+[[Category: Unno H]]
-[[Category: Sulfolobus shibatae]]
+[[Category: Yamashita S]]
-[[Category: Hemmi, H.]]
+[[Category: Yoshida N]]
-[[Category: Ikeda, Y.]]
+[[Category: Yoshimura T]]
-[[Category: Kusunoki, M.]]
-[[Category: Nakayama, T.]]
-[[Category: Nishino, T.]]
-[[Category: Sekiguchi, S.]]
-[[Category: Unno, H.]]
-[[Category: Yamashita, S.]]
-[[Category: Yoshida, N.]]
-[[Category: Yoshimura, T.]]
-[[Category: Flavoprotein]]
-[[Category: Fmn]]
-[[Category: Idi]]
-[[Category: Isomerase]]
-[[Category: Isopentenyl diphosphate isomerase]]
-[[Category: Isoprene biosynthesis]]
-[[Category: Nadp]]
-[[Category: Reduced form]]
-[[Category: Type 2]]