2iob: Difference between revisions

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{{Seed}}
[[Image:2iob.png|left|200px]]


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==E. coli Bifunctional glutathionylspermidine synthetase/amidase Apo protein==
The line below this paragraph, containing "STRUCTURE_2iob", creates the "Structure Box" on the page.
<StructureSection load='2iob' size='340' side='right'caption='[[2iob]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2iob]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IOB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IOB FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iob OCA], [https://pdbe.org/2iob PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iob RCSB], [https://www.ebi.ac.uk/pdbsum/2iob PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iob ProSAT]</span></td></tr>
{{STRUCTURE_2iob|  PDB=2iob  |  SCENE=  }}
</table>
 
== Function ==
===E. coli Bifunctional glutathionylspermidine synthetase/amidase Apo protein===
[https://www.uniprot.org/uniprot/GSP_ECOLI GSP_ECOLI] Catalyzes the formation of an amide bond between glutathione and spermidine coupled with hydrolysis of ATP; also catalyzes the hydrolysis of glutathionylspermidine to glutathione and spermidine.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/io/2iob_consurf.spt"</scriptWhenChecked>
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    <text>to colour the structure by Evolutionary Conservation</text>
 
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==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iob ConSurf].
2IOB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IOB OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase., Pai CH, Chiang BY, Ko TP, Chou CC, Chong CM, Yen FJ, Chen S, Coward JK, Wang AH, Lin CH, EMBO J. 2006 Dec 13;25(24):5970-82. Epub 2006 Nov 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17124497 17124497]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Chiang, B Y.]]
[[Category: Chiang BY]]
[[Category: Chong, C M.]]
[[Category: Chong CM]]
[[Category: Chou, C C.]]
[[Category: Chou CC]]
[[Category: Coward, J K.]]
[[Category: Coward JK]]
[[Category: Ko, T P.]]
[[Category: Ko TP]]
[[Category: Lin, C H.]]
[[Category: Lin CH]]
[[Category: Pai, C H.]]
[[Category: Pai CH]]
[[Category: Wang, A H.J.]]
[[Category: Wang AH-J]]
[[Category: Yen, F J.]]
[[Category: Yen FJ]]
[[Category: Bifunctional glutathionylspermidine synthetase/amidase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 04:00:18 2008''

Latest revision as of 16:52, 13 March 2024

E. coli Bifunctional glutathionylspermidine synthetase/amidase Apo proteinE. coli Bifunctional glutathionylspermidine synthetase/amidase Apo protein

Structural highlights

2iob is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GSP_ECOLI Catalyzes the formation of an amide bond between glutathione and spermidine coupled with hydrolysis of ATP; also catalyzes the hydrolysis of glutathionylspermidine to glutathione and spermidine.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2iob, resolution 2.20Å

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