2dul: Difference between revisions

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-{{Seed}}
-[[Image:2dul.png|left|200px]]
-<!--
+==Crystal structure of tRNA G26 methyltransferase Trm1 in apo form from Pyrococcus horikoshii==
-The line below this paragraph, containing "STRUCTURE_2dul", creates the "Structure Box" on the page.
+<StructureSection load='2dul' size='340' side='right'caption='[[2dul]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2dul]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DUL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DUL FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-{{STRUCTURE_2dul|  PDB=2dul  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dul FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dul OCA], [https://pdbe.org/2dul PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dul RCSB], [https://www.ebi.ac.uk/pdbsum/2dul PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dul ProSAT], [https://www.topsan.org/Proteins/RSGI/2dul TOPSAN]</span></td></tr>
+</table>
-===Crystal structure of tRNA G26 methyltransferase Trm1 in apo form from Pyrococcus horikoshii===
+== Function ==
+[https://www.uniprot.org/uniprot/TRM1_PYRHO TRM1_PYRHO] Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups (By similarity).
+== Evolutionary Conservation ==
-<!--
+[[Image:Consurf_key_small.gif|200px|right]]
-The line below this paragraph, {{ABSTRACT_PUBMED_18789948}}, adds the Publication Abstract to the page
+Check<jmol>
-(as it appears on PubMed at http://www.pubmed.gov), where 18789948 is the PubMed ID number.
+  <jmolCheckbox>
--->
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/du/2dul_consurf.spt"</scriptWhenChecked>
-{{ABSTRACT_PUBMED_18789948}}
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
-==About this Structure==
+  </jmolCheckbox>
-DUL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DUL OCA].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dul ConSurf].
+<div style="clear:both"></div>
-==Reference==
+__TOC__
-Crystal structure of tRNA N2,N2-guanosine dimethyltransferase Trm1 from Pyrococcus horikoshii., Ihsanawati, Nishimoto M, Higashijima K, Shirouzu M, Grosjean H, Bessho Y, Yokoyama S, J Mol Biol. 2008 Nov 21;383(4):871-84. Epub 2008 Sep 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18789948 18789948]
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Pyrococcus horikoshii]]
-[[Category: Single protein]]
+[[Category: Bessho Y]]
-[[Category: Bessho, Y.]]
 [[Category: Ihsanawati]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+[[Category: Shirouzu M]]
-[[Category: Shirouzu, M.]]
+[[Category: Yokoyama S]]
-[[Category: Yokoyama, S.]]
-[[Category: Guanine 26]]
-[[Category: National project on protein structural and functional analyse]]
-[[Category: Nppsfa]]
-[[Category: Riken structural genomics/proteomics initiative]]
-[[Category: Rsgi]]
-[[Category: Structural genomic]]
-[[Category: Trna modification enzyme]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 22 09:46:07 2008''