2dul: Difference between revisions
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==Crystal structure of tRNA G26 methyltransferase Trm1 in apo form from Pyrococcus horikoshii== | |||
<StructureSection load='2dul' size='340' side='right'caption='[[2dul]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
| | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2dul]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DUL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DUL FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dul FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dul OCA], [https://pdbe.org/2dul PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dul RCSB], [https://www.ebi.ac.uk/pdbsum/2dul PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dul ProSAT], [https://www.topsan.org/Proteins/RSGI/2dul TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TRM1_PYRHO TRM1_PYRHO] Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups (By similarity). | |||
== Evolutionary Conservation == | |||
== | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/du/2dul_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dul ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Pyrococcus horikoshii]] | [[Category: Pyrococcus horikoshii]] | ||
[[Category: Bessho Y]] | |||
[[Category: Bessho | |||
[[Category: Ihsanawati]] | [[Category: Ihsanawati]] | ||
[[Category: Shirouzu M]] | |||
[[Category: Shirouzu | [[Category: Yokoyama S]] | ||
[[Category: Yokoyama | |||
Latest revision as of 16:48, 13 March 2024
Crystal structure of tRNA G26 methyltransferase Trm1 in apo form from Pyrococcus horikoshiiCrystal structure of tRNA G26 methyltransferase Trm1 in apo form from Pyrococcus horikoshii
Structural highlights
FunctionTRM1_PYRHO Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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