2csx: Difference between revisions

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-[[Image:2csx.gif|left|200px]]
- {{Structure
+==Crystal structure of Aquifex aeolicus methionyl-tRNA synthetase complexed with tRNA(Met)==
-|PDB= 2csx |SIZE=350|CAPTION= <scene name='initialview01'>2csx</scene>, resolution 2.70&Aring;
+<StructureSection load='2csx' size='340' side='right'caption='[[2csx]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>
+<table><tr><td colspan='2'>[[2csx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CSX FirstGlance]. <br>
-|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine--tRNA_ligase Methionine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.10 6.1.1.10] </span>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-|GENE=
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2csx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2csx OCA], [https://pdbe.org/2csx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2csx RCSB], [https://www.ebi.ac.uk/pdbsum/2csx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2csx ProSAT], [https://www.topsan.org/Proteins/RSGI/2csx TOPSAN]</span></td></tr>
-|DOMAIN=
+</table>
-|RELATEDENTRY=[[2ct8|2CT8]]
+== Function ==
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2csx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2csx OCA], [http://www.ebi.ac.uk/pdbsum/2csx PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2csx RCSB]</span>
+[https://www.uniprot.org/uniprot/SYM_AQUAE SYM_AQUAE] Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity).
-}}
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cs/2csx_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2csx ConSurf].
+<div style="clear:both"></div>
-'''Crystal structure of Aquifex aeolicus methionyl-tRNA synthetase complexed with tRNA(Met)'''
+==See Also==
+*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
+*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]]
-==About this Structure==
+__TOC__
-CSX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSX OCA].
+</StructureSection>
 [[Category: Aquifex aeolicus]]
-[[Category: Methionine--tRNA ligase]]
+[[Category: Large Structures]]
-[[Category: Single protein]]
+[[Category: Fukai S]]
-[[Category: Fukai, S.]]
+[[Category: Nakama T]]
-[[Category: Nakama, T.]]
+[[Category: Nakanishi K]]
-[[Category: Nakanishi, K.]]
+[[Category: Nureki O]]
-[[Category: Nureki, O.]]
+[[Category: Ogiso Y]]
-[[Category: Ogiso, Y.]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
-[[Category: ligase]]
-[[Category: riken structural genomics/proteomics initiative]]
-[[Category: rsgi]]
-[[Category: structural genomic]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:26:00 2008''