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[[Image:2b7n.gif|left|200px]]


{{Structure
==Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori==
|PDB= 2b7n |SIZE=350|CAPTION= <scene name='initialview01'>2b7n</scene>, resolution 2.30&Aring;
<StructureSection load='2b7n' size='340' side='right'caption='[[2b7n]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=NTM:QUINOLINIC ACID'>NTM</scene>
<table><tr><td colspan='2'>[[2b7n]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B7N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B7N FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Nicotinate-nucleotide_diphosphorylase_(carboxylating) Nicotinate-nucleotide diphosphorylase (carboxylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.19 2.4.2.19]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NTM:QUINOLINIC+ACID'>NTM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b7n OCA], [https://pdbe.org/2b7n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b7n RCSB], [https://www.ebi.ac.uk/pdbsum/2b7n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b7n ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NADC_HELPY NADC_HELPY] Involved in the catabolism of quinolinic acid (QA) (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b7/2b7n_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b7n ConSurf].
<div style="clear:both"></div>


'''Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori'''
==See Also==
 
*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2B7N is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B7N OCA].
 
==Reference==
Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori., Kim MK, Im YJ, Lee JH, Eom SH, Proteins. 2006 Apr 1;63(1):252-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16419067 16419067]
[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
[[Category: Nicotinate-nucleotide diphosphorylase (carboxylating)]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Eom SH]]
[[Category: Eom, S H.]]
[[Category: Im YJ]]
[[Category: Im, Y J.]]
[[Category: Kim MK]]
[[Category: Kim, M K.]]
[[Category: Lee JH]]
[[Category: Lee, J H.]]
[[Category: NTM]]
[[Category: SO4]]
[[Category: helicobacter pylori]]
[[Category: quinolinate phosphoribosyltransferase]]
[[Category: quinolinic acid]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:58:33 2008''

Latest revision as of 16:42, 13 March 2024

Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pyloriCrystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori

Structural highlights

2b7n is a 3 chain structure with sequence from Helicobacter pylori. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NADC_HELPY Involved in the catabolism of quinolinic acid (QA) (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2b7n, resolution 2.30Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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