2adv: Difference between revisions
New page: left|200px<br /><applet load="2adv" size="450" color="white" frame="true" align="right" spinBox="true" caption="2adv, resolution 2.244Å" /> '''Crystal Structures ... |
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== | ==Crystal Structures Of Glutaryl 7-Aminocephalosporanic Acid Acylase: mutational study of activation mechanism== | ||
<StructureSection load='2adv' size='340' side='right'caption='[[2adv]], [[Resolution|resolution]] 2.24Å' scene=''> | |||
[ | == Structural highlights == | ||
[[ | <table><tr><td colspan='2'>[[2adv]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._GK16 Pseudomonas sp. GK16]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ADV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ADV FirstGlance]. <br> | ||
[[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.244Å</td></tr> | ||
[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2adv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2adv OCA], [https://pdbe.org/2adv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2adv RCSB], [https://www.ebi.ac.uk/pdbsum/2adv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2adv ProSAT]</span></td></tr> | ||
[ | </table> | ||
[ | == Function == | ||
[ | [https://www.uniprot.org/uniprot/G7AC_PSEU7 G7AC_PSEU7] Catalyzes the deacylation of 7 beta-(4-carboxybutanamido)cephalosporanic acid (glutaryl-7-aminocephalosporanic acid or GL-7-ACA) to 7-aminocephalosporanic acid (7-ACA).<ref>PMID:2993240</ref> | ||
[ | == Evolutionary Conservation == | ||
[ | [[Image:Consurf_key_small.gif|200px|right]] | ||
[[ | Check<jmol> | ||
<jmolCheckbox> | |||
[ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ad/2adv_consurf.spt"</scriptWhenChecked> | ||
[[ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
[ | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2adv ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Cephalosporin acylase 3D structures|Cephalosporin acylase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Pseudomonas sp. GK16]] | |||
[[Category: Cho KJ]] | |||
[[Category: Kim JK]] | |||
[[Category: Kim KH]] | |||
[[Category: Kim SH]] | |||
[[Category: Park SS]] | |||
[[Category: Ryu EK]] | |||
[[Category: Shin HJ]] | |||
[[Category: Yang IS]] | |||
