2a4x: Difference between revisions

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[[Image:2a4x.png|left|200px]]


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==Crystal Structure Of Mitomycin C-Binding Protein Complexed with Metal-Free Bleomycin A2==
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<StructureSection load='2a4x' size='340' side='right'caption='[[2a4x]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2a4x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_caespitosus Streptomyces caespitosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A4X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A4X FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BLM:BLEOMYCIN+A2'>BLM</scene></td></tr>
{{STRUCTURE_2a4x|  PDB=2a4x  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a4x OCA], [https://pdbe.org/2a4x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a4x RCSB], [https://www.ebi.ac.uk/pdbsum/2a4x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a4x ProSAT]</span></td></tr>
 
</table>
===Crystal Structure Of Mitomycin C-Binding Protein Complexed with Metal-Free Bleomycin A2===
== Function ==
 
[https://www.uniprot.org/uniprot/O05205_STRLA O05205_STRLA]
 
== Evolutionary Conservation ==
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a4/2a4x_consurf.spt"</scriptWhenChecked>
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
2A4X is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_caespitosus Streptomyces caespitosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A4X OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a4x ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
The mitomycin C (MMC)-binding protein from MMC-producing microorganisms protects from the lethal effect of bleomycin: crystallographic analysis to elucidate the binding mode of the antibiotic to the protein., Danshiitsoodol N, de Pinho CA, Matoba Y, Kumagai T, Sugiyama M, J Mol Biol. 2006 Jul 7;360(2):398-408. Epub 2006 May 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16756991 16756991]
</StructureSection>
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Streptomyces caespitosus]]
[[Category: Streptomyces caespitosus]]
[[Category: Danshiitsoodol, N.]]
[[Category: Danshiitsoodol N]]
[[Category: Kumagai, T.]]
[[Category: Kumagai T]]
[[Category: Matoba, Y.]]
[[Category: Matoba Y]]
[[Category: Pinho, C A.de.]]
[[Category: Sugiyama M]]
[[Category: Sugiyama, M.]]
[[Category: De Pinho CA]]
[[Category: Alfa/beta protein]]
[[Category: Bleomycin a2]]
[[Category: Mitomycin c-binding protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 20:29:22 2008''

Latest revision as of 16:40, 13 March 2024

Crystal Structure Of Mitomycin C-Binding Protein Complexed with Metal-Free Bleomycin A2Crystal Structure Of Mitomycin C-Binding Protein Complexed with Metal-Free Bleomycin A2

Structural highlights

2a4x is a 2 chain structure with sequence from Streptomyces caespitosus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.4Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

O05205_STRLA

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2a4x, resolution 1.40Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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