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==Crystal Structure Analysis of a 6-coordinated Cytochorome P450 from Thermus thermophilus HB8== | ==Crystal Structure Analysis of a 6-coordinated Cytochorome P450 from Thermus thermophilus HB8== | ||
<StructureSection load='1wiy' size='340' side='right' caption='[[1wiy]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='1wiy' size='340' side='right'caption='[[1wiy]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1wiy]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1wiy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WIY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WIY FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wiy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wiy OCA], [https://pdbe.org/1wiy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wiy RCSB], [https://www.ebi.ac.uk/pdbsum/1wiy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wiy ProSAT], [https://www.topsan.org/Proteins/RSGI/1wiy TOPSAN]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/Q53W59_THET8 Q53W59_THET8] | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wi/1wiy_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wi/1wiy_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wiy ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Cytochrome P450|Cytochrome P450]] | *[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Kaneko | [[Category: Thermus thermophilus]] | ||
[[Category: Kousumi | [[Category: Kaneko M]] | ||
[[Category: Kuramitsu | [[Category: Kousumi Y]] | ||
[[Category: Masui | [[Category: Kuramitsu S]] | ||
[[Category: Nakagawa | [[Category: Masui R]] | ||
[[Category: Nakagawa N]] | |||
[[Category: Ueyama | [[Category: Ueyama N]] | ||
[[Category: Yamamoto | [[Category: Yamamoto H]] | ||
Latest revision as of 16:31, 13 March 2024
Crystal Structure Analysis of a 6-coordinated Cytochorome P450 from Thermus thermophilus HB8Crystal Structure Analysis of a 6-coordinated Cytochorome P450 from Thermus thermophilus HB8
Structural highlights
FunctionEvolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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