1wf3: Difference between revisions

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-[[Image:1wf3.jpg|left|200px]]
-<!--
+==Crystal structure of GTP-binding protein TT1341 from Thermus thermophilus HB8==
-The line below this paragraph, containing "STRUCTURE_1wf3", creates the "Structure Box" on the page.
+<StructureSection load='1wf3' size='340' side='right'caption='[[1wf3]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1wf3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WF3 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-{{STRUCTURE_1wf3|  PDB=1wf3  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wf3 OCA], [https://pdbe.org/1wf3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wf3 RCSB], [https://www.ebi.ac.uk/pdbsum/1wf3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wf3 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wf3 TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ERA_THET8 ERA_THET8] An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity).  The Era binding site on the 30S subunit overlaps that of protein S1 and is in direct contact with 5 nucleotides directly upstream of the anti-Shine-Dalgarno sequence; the presence of Era may prevent mRNA recruitment. 30S subunits bound to Era are not able to bind to the 50S subunit to make functional ribosomes. Era may serve a role in the final stages of 30S ribosomal subunit assembly.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wf/1wf3_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wf3 ConSurf].
+<div style="clear:both"></div>
-'''Crystal structure of GTP-binding protein TT1341 from Thermus thermophilus HB8'''
+==See Also==
+*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
+__TOC__
-==About this Structure==
+</StructureSection>
-Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WF3 OCA].
+[[Category: Large Structures]]
-[[Category: Hori-Takemoto, C.]]
+[[Category: Thermus thermophilus HB8]]
-[[Category: Kaminishi, T.]]
+[[Category: Hori-Takemoto C]]
-[[Category: Kawazoe, M.]]
+[[Category: Kaminishi T]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+[[Category: Kawazoe M]]
-[[Category: Sekine, S.]]
+[[Category: Sekine S]]
-[[Category: Shirouzu, M.]]
+[[Category: Shirouzu M]]
-[[Category: Yokoyama, S.]]
+[[Category: Yokoyama S]]
-[[Category: Gtp-binding protein]]
-[[Category: Gtpase]]
-[[Category: Riken structural genomics/proteomics initiative]]
-[[Category: Rsgi]]
-[[Category: Structural genomic]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 13:34:01 2008''