1wcw: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-[[Image:1wcw.gif|left|200px]]<br /><applet load="1wcw" size="450" color="white" frame="true" align="right" spinBox="true"
-caption="1wcw, resolution 1.3&Aring;" />
-'''Crystal Structure of Uroporphyrinogen III Synthase from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 (Wild type, Native, Form-1 crystal)'''<br />
-==About this Structure==
+==Crystal Structure of Uroporphyrinogen III Synthase from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 (Wild type, Native, Form-1 crystal)==
-WCW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with GOL as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Uroporphyrinogen-III_synthase Uroporphyrinogen-III synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.75 4.2.1.75] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1WCW OCA].
+<StructureSection load='1wcw' size='340' side='right'caption='[[1wcw]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
-[[Category: Single protein]]
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1wcw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WCW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WCW FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wcw OCA], [https://pdbe.org/1wcw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wcw RCSB], [https://www.ebi.ac.uk/pdbsum/1wcw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wcw ProSAT], [https://www.topsan.org/Proteins/RSGI/1wcw TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q5SKH2_THET8 Q5SKH2_THET8]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wc/1wcw_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wcw ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Thermus thermophilus]]
-[[Category: Uroporphyrinogen-III synthase]]
+[[Category: Kuramitsu S]]
-[[Category: Kuramitsu, S.]]
+[[Category: Matsuura T]]
-[[Category: Matsuura, T.]]
+[[Category: Mizohata E]]
-[[Category: Mizohata, E.]]
+[[Category: Murayama K]]
-[[Category: Murayama, K.]]
+[[Category: Sakai H]]
-[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
+[[Category: Shirouzu M]]
-[[Category: Sakai, H.]]
+[[Category: Terada T]]
-[[Category: Shirouzu, M.]]
+[[Category: Yokoyama S]]
-[[Category: Terada, T.]]
-[[Category: Yokoyama, S.]]
-[[Category: GOL]]
-[[Category: congenital erythropoietic porphyria]]
-[[Category: porphyrin]]
-[[Category: riken structural genomics/proteomics initiative]]
-[[Category: rsgi]]
-[[Category: structural genomics]]
-[[Category: uroporphyrinogen]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sat Nov 24 23:44:40 2007''