1u09: Difference between revisions

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[[Image:1u09.png|left|200px]]


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==Footand Mouth Disease Virus RNA-dependent RNA polymerase==
The line below this paragraph, containing "STRUCTURE_1u09", creates the "Structure Box" on the page.
<StructureSection load='1u09' size='340' side='right'caption='[[1u09]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1u09]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Foot-and-mouth_disease_virus_C-S8c1 Foot-and-mouth disease virus C-S8c1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U09 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U09 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.91&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u09 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u09 OCA], [https://pdbe.org/1u09 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u09 RCSB], [https://www.ebi.ac.uk/pdbsum/1u09 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u09 ProSAT]</span></td></tr>
{{STRUCTURE_1u09|  PDB=1u09  |  SCENE=  }}
</table>
 
== Function ==
===Footand Mouth Disease Virus RNA-dependent RNA polymerase===
[https://www.uniprot.org/uniprot/Q9QCE4_9PICO Q9QCE4_9PICO] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266]  RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047]
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u09 ConSurf].
1U09 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Foot-and-mouth_disease_virus Foot-and-mouth disease virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U09 OCA].  
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__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:15294895</ref><references group="xtra"/>
[[Category: Foot-and-mouth disease virus C-S8c1]]
[[Category: Foot-and-mouth disease virus]]
[[Category: Large Structures]]
[[Category: RNA-directed RNA polymerase]]
[[Category: Arias A]]
[[Category: Arias, A.]]
[[Category: Domingo E]]
[[Category: Domingo, E.]]
[[Category: Escarmis C]]
[[Category: Escarmis, C.]]
[[Category: Ferrer-Orta C]]
[[Category: Ferrer-Orta, C.]]
[[Category: Perez-Luque R]]
[[Category: Perez-Luque, R.]]
[[Category: Verdaguer N]]
[[Category: Verdaguer, N.]]
[[Category: Foot and mouth disease virus]]
[[Category: Protein-dna complex]]
[[Category: Rna-dependent rna polymerase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 08:16:51 2009''

Latest revision as of 16:30, 13 March 2024

Footand Mouth Disease Virus RNA-dependent RNA polymeraseFootand Mouth Disease Virus RNA-dependent RNA polymerase

Structural highlights

1u09 is a 1 chain structure with sequence from Foot-and-mouth disease virus C-S8c1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.91Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q9QCE4_9PICO Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1u09, resolution 1.91Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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