1tlx: Difference between revisions

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[[Image:1tlx.png|left|200px]]


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==THERMOLYSIN (NATIVE)==
The line below this paragraph, containing "STRUCTURE_1tlx", creates the "Structure Box" on the page.
<StructureSection load='1tlx' size='340' side='right'caption='[[1tlx]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1tlx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TLX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TLX FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=VAL:VALINE'>VAL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_1tlx|  PDB=1tlx  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tlx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tlx OCA], [https://pdbe.org/1tlx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tlx RCSB], [https://www.ebi.ac.uk/pdbsum/1tlx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tlx ProSAT]</span></td></tr>
 
</table>
===THERMOLYSIN (NATIVE)===
== Function ==
 
[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH] Extracellular zinc metalloprotease.
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_10651278}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 10651278 is the PubMed ID number.
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tl/1tlx_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_10651278}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
[[1tlx]] is a 1 chain structure of [[Thermolysin]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TLX OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tlx ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Thermolysin]]
*[[Thermolysin 3D structures|Thermolysin 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:10651278</ref><references group="xtra"/>
[[Category: Bacillus thermoproteolyticus]]
[[Category: Bacillus thermoproteolyticus]]
[[Category: Thermolysin]]
[[Category: Large Structures]]
[[Category: Done, S H.]]
[[Category: Done SH]]
[[Category: English, A C.]]
[[Category: English AC]]
[[Category: Groom, C R.]]
[[Category: Groom CR]]
[[Category: Hubbard, R E.]]
[[Category: Hubbard RE]]
[[Category: Hydrolase]]
[[Category: Metalloproteinase]]
[[Category: Organic solvent]]

Latest revision as of 16:30, 13 March 2024

THERMOLYSIN (NATIVE)THERMOLYSIN (NATIVE)

Structural highlights

1tlx is a 1 chain structure with sequence from Bacillus thermoproteolyticus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Ligands:, , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

THER_BACTH Extracellular zinc metalloprotease.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1tlx, resolution 2.10Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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