1lp4: Difference between revisions

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-[[Image:1lp4.png|left|200px]]
-{{STRUCTURE_1lp4|  PDB=1lp4  |  SCENE=  }}
+==Crystal structure of a binary complex of the catalytic subunit of protein kinase CK2 with Mg-AMPPNP==
+<StructureSection load='1lp4' size='340' side='right'caption='[[1lp4]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
-===Crystal structure of a binary complex of the catalytic subunit of protein kinase CK2 with Mg-AMPPNP===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1lp4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LP4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LP4 FirstGlance]. <br>
-{{ABSTRACT_PUBMED_15740749}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lp4 OCA], [https://pdbe.org/1lp4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lp4 RCSB], [https://www.ebi.ac.uk/pdbsum/1lp4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lp4 ProSAT]</span></td></tr>
-[[1lp4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LP4 OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CSK2A_MAIZE CSK2A_MAIZE] Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lp/1lp4_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lp4 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Casein kinase|Casein kinase]]
+*[[Casein kinase 3D structures|Casein kinase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:015740749</ref><ref group="xtra">PMID:009564028</ref><ref group="xtra">PMID:009761839</ref><ref group="xtra">PMID:010581548</ref><ref group="xtra">PMID:011574463</ref><references group="xtra"/>
+[[Category: Large Structures]]
-[[Category: Non-specific serine/threonine protein kinase]]
 [[Category: Zea mays]]
-[[Category: Guerra, B.]]
+[[Category: Guerra B]]
-[[Category: Issinger, O G.]]
+[[Category: Issinger O-G]]
-[[Category: Niefind, K.]]
+[[Category: Niefind K]]
-[[Category: Puetter, M.]]
+[[Category: Puetter M]]
-[[Category: Schomburg, D.]]
+[[Category: Schomburg D]]
-[[Category: Casein kinase 2]]
-[[Category: Ck2]]
-[[Category: Dual-cosubstrate specificity]]
-[[Category: Protein kinase]]
-[[Category: Transferase]]