1jqo: Difference between revisions

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-[[Image:1jqo.jpg|left|200px]]
-<!--
+==Crystal structure of C4-form phosphoenolpyruvate carboxylase from maize==
-The line below this paragraph, containing "STRUCTURE_1jqo", creates the "Structure Box" on the page.
+<StructureSection load='1jqo' size='340' side='right'caption='[[1jqo]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1jqo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JQO FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-{{STRUCTURE_1jqo|  PDB=1jqo  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jqo OCA], [https://pdbe.org/1jqo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jqo RCSB], [https://www.ebi.ac.uk/pdbsum/1jqo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jqo ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CAPP1_MAIZE CAPP1_MAIZE] Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jq/1jqo_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jqo ConSurf].
+<div style="clear:both"></div>
-'''Crystal structure of C4-form phosphoenolpyruvate carboxylase from maize'''
+==See Also==
+*[[Phosphoenolpyruvate carboxylase|Phosphoenolpyruvate carboxylase]]
+__TOC__
-==Overview==
+</StructureSection>
-Phosphoenolpyruvate carboxylase (PEPC) catalyzes the first step in the fixation of atmospheric CO(2) during C(4) photosynthesis. The crystal structure of C(4) form maize PEPC (ZmPEPC), the first structure of the plant PEPCs, has been determined at 3.0 A resolution. The structure includes a sulfate ion at the plausible binding site of an allosteric activator, glucose 6-phosphate. The crystal structure of E. coli PEPC (EcPEPC) complexed with Mn(2+), phosphoenolpyruvate analog (3,3-dichloro-2-dihydroxyphosphinoylmethyl-2-propenoate), and an allosteric inhibitor, aspartate, has also been determined at 2.35 A resolution. Dynamic movements were found in the ZmPEPC structure, compared with the EcPEPC structure, around two loops near the active site. On the basis of these molecular structures, the mechanisms for the carboxylation reaction and for the allosteric regulation of PEPC are proposed.
+[[Category: Large Structures]]
-==About this Structure==
-JQO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQO OCA].
-==Reference==
-Crystal structures of C4 form maize and quaternary complex of E. coli phosphoenolpyruvate carboxylases., Matsumura H, Xie Y, Shirakata S, Inoue T, Yoshinaga T, Ueno Y, Izui K, Kai Y, Structure. 2002 Dec;10(12):1721-30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12467579 12467579]
-[[Category: Phosphoenolpyruvate carboxylase]]
-[[Category: Single protein]]
 [[Category: Zea mays]]
-[[Category: Kai, Y.]]
+[[Category: Kai Y]]
-[[Category: Matsumura, H.]]
+[[Category: Matsumura H]]
-[[Category: Beta barrel]]
-[[Category: Carbon dioxide fixation]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 21:40:35 2008''