5t4x: Difference between revisions

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-'''Unreleased structure'''
-The entry 5t4x is ON HOLD  until Paper Publication
+==CRYSTAL STRUCTURE OF PDE6D IN APO-STATE==
+<StructureSection load='5t4x' size='340' side='right'caption='[[5t4x]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5t4x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T4X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5T4X FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.81&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5t4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t4x OCA], [https://pdbe.org/5t4x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5t4x RCSB], [https://www.ebi.ac.uk/pdbsum/5t4x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5t4x ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PDE6D_MOUSE PDE6D_MOUSE] Promotes the release of prenylated target proteins from cellular membranes (PubMed:22179043). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (PubMed:22179043). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (PubMed:22179043). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.[UniProtKB:O43924][UniProtKB:Q95142]<ref>PMID:10518933</ref> <ref>PMID:15979089</ref> <ref>PMID:22179043</ref>
-Authors: Qureshi, B.M., Schmidt, A., Scheerer, P.
+==See Also==
+*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
-Description: CRYSTAL STRUCTURE OF PDE6D IN APO-STATE
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
-[[Category: Qureshi, B.M]]
+__TOC__
-[[Category: Scheerer, P]]
+</StructureSection>
-[[Category: Schmidt, A]]
+[[Category: Large Structures]]
+[[Category: Mus musculus]]
+[[Category: Qureshi BM]]
+[[Category: Scheerer P]]
+[[Category: Schmidt A]]