5t47: Difference between revisions
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==Crystal structure of the D. melanogaster eIF4E-eIF4G complex== | |||
<StructureSection load='5t47' size='340' side='right'caption='[[5t47]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5t47]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T47 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5T47 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5t47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t47 OCA], [https://pdbe.org/5t47 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5t47 RCSB], [https://www.ebi.ac.uk/pdbsum/5t47 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5t47 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/IF4E_DROME IF4E_DROME] Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.<ref>PMID:8663200</ref> | |||
==See Also== | |||
*[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Drosophila melanogaster]] | |||
[[Category: Large Structures]] | |||
[[Category: Chung M-Y]] | |||
[[Category: Gruener S]] | |||
[[Category: Igreja C]] | |||
[[Category: Izaurralde E]] | |||
[[Category: Peter D]] | |||
[[Category: Valkov E]] | |||
[[Category: Weber R]] | |||
[[Category: Weichenrieder O]] | |||
[[Category: Wohlbold L]] |