6wz9: Difference between revisions

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OCA

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-====
+==Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin==
-<StructureSection load='6wz9' size='340' side='right'caption='[[6wz9]]' scene=''>
+<StructureSection load='6wz9' size='340' side='right'caption='[[6wz9]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6wz9]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WZ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WZ9 FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6wz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wz9 OCA], [http://pdbe.org/6wz9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6wz9 RCSB], [http://www.ebi.ac.uk/pdbsum/6wz9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6wz9 ProSAT]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wz9 OCA], [https://pdbe.org/6wz9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wz9 RCSB], [https://www.ebi.ac.uk/pdbsum/6wz9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wz9 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/H4_XENLA H4_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
+==See Also==
+*[[Histone 3D structures|Histone 3D structures]]
 __TOC__
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Z-disk]]
+[[Category: Synthetic construct]]
+[[Category: Xenopus laevis]]
+[[Category: Bilokapic S]]
+[[Category: Halic M]]