6utg: Difference between revisions
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The | ==Allosteric coupling between alpha-rings of the 20S proteasome, 20S singly capped with a PA26/V230F== | ||
<StructureSection load='6utg' size='340' side='right'caption='[[6utg]], [[Resolution|resolution]] 3.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6utg]] is a 35 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum] and [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UTG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UTG FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6utg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6utg OCA], [https://pdbe.org/6utg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6utg RCSB], [https://www.ebi.ac.uk/pdbsum/6utg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6utg ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PSA_THEAC PSA_THEAC] Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The T.acidophilum proteasome is able to cleave oligopeptides after Tyr, Leu, Phe, and to a lesser extent after Glu and Arg. Thus, displays chymotrypsin-like activity and low level of caspase-like and trypsin-like activities.<ref>PMID:8999862</ref> | |||
==See Also== | |||
*[[Proteasome 3D structures|Proteasome 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: Cheng | __TOC__ | ||
[[Category: Yu | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Thermoplasma acidophilum]] | |||
[[Category: Trypanosoma brucei]] | |||
[[Category: Cheng Y]] | |||
[[Category: Yu Z]] |