5te1: Difference between revisions

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OCA

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-'''Unreleased structure'''
-The entry 5te1 is ON HOLD
+==C20S, C293G Mutant N-terminal Human ATP Citrate Lyase Bound to 4R-Hydroxycitrate==
+<StructureSection load='5te1' size='340' side='right'caption='[[5te1]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5te1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TE1 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7A2:3-C-carboxy-2-deoxy-L-threo-pentaric+acid'>7A2</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5te1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5te1 OCA], [https://pdbe.org/5te1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5te1 RCSB], [https://www.ebi.ac.uk/pdbsum/5te1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5te1 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ACLY_HUMAN ACLY_HUMAN] ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.<ref>PMID:23932781</ref>
-Authors: Hu, J., Fraser, M.E.
+==See Also==
+*[[ATP-citrate synthase 3D structures|ATP-citrate synthase 3D structures]]
-Description: C20S C293G Mutate N-ternimal Human ATP Citrate Lyase bound to 4R Hydroxycitrate
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
-[[Category: Fraser, M.E]]
+__TOC__
-[[Category: Hu, J]]
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Fraser ME]]
+[[Category: Hu J]]